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First of all make sure your suggested skill leveling is possible (You can't do E/W/E/E/E as the maximum lvl of an ability is restricted at that point)
2nd if you are going with tanky builds that used lots of AD it's better to get Rylai so you can actually do some DMG and vamp with the spells. Randuin is just bad compared to a rylai if you have another source of armor already.
3rd The healing 8% mastery is way better over the puny 45 max HP one.
The list goes on but I shall stop here.