Not Updated For Current Season
The masteries shown here are not yet updated for the current season, the guide author needs to set up the new masteries. As such, they will be different than the masteries you see in-game.
Akali is a very squishy champion, so make sure you lane with a tank. If you can't lane with a tank, lane with a heavy champion such as Dr. Mundo or Pantheon. Your first skill is usually Mark of the Assassin, but you can change it up depending on your lane enemies. Early game, rush Frozen Mallet. Around level 7~8, as long as you have a decent lane partner, you should have about 2 kills, and enough for Frozen Mallet or at least Phage + Giant's belt. When you get Frozen Mallet, start ganking. The hp makes you harder to kill, and the slow makes sure they can't run away. Get back to base and buy your boots and start on Guinsoo's Rageblade. This item was made for Akali. It benefits your passive beautifully. Mid game (10-15) You should be ganking the hell out of the other team. You should have at least 8 kills, and less than 3 deaths if you're playing right. I don't get Mejai Soulstealer or Sword of the Occult because I never know how well I'm gonna do in a game, but it's an option if you want it. Finish your build and keep ganking. You should be invincible 1v1 (Practically) and be able to push turrets fairly well. Late game should never even arrive as they'll be bowing to defeat within 25 minutes