Not Updated For Current Season
The masteries shown here are not yet updated for the current season, the guide author needs to set up the new masteries. As such, they will be different than the masteries you see in-game.
This is actually a descent build because it also puts health and other things that Vlad uses as well as cool downs, the reason i use cool downs is because that way his transfusion has a one second cool down and his sanguine pool is also very short. because of his short transfusion Vladimir practically never runs out of health, I admit he gets low but just use transfusion 10 times, sanguine pool and yay! full health.