Wanna be unkillable? then use my build!!! And with his cleaver alone i get about 10 kills early!!!

Pros:
almost unkillable
cleaver=lots of damage
lots of others i can't think of at the moment
Cons:
not large damage output

With my runes i go with health and health regen so you already have some base of each. i use tank masteries because he is kinda one! with items i start with first part to warthogs armour and heath potion so i can stay in battle for a long time, next buy Spirit Visage cuz of passive (increase of healing affects),then buy boots that reduce cc time, then finish warthogs, then buy force of nature for health regain and movement speed, then grab sunfire cape for more damage then sell spirit visage for 1 last warthogs so you are almost unkillable even if all 5 of them target you!!! max out cleaver early so you can harrass like crazy but dont get killed cuz the key to mundo is not getting killed. then grab ult whenever possible, then finish with 2nd and 3rd abilities.

harrass=good game
die=not good outcome

(fallow tht and pwn! ;)