This is my tipical build of Vayne. I buy guardian angel at 3th slot because i like to hunt enemy :)

this is my skill sequence

Every time is possible use Tumble

When you learn Condemn at 3rd level, use it to push away from you the enemy hero, and if you can try to push him on wall to stun

When you are 6th level and you want to kill a enemy Hero you need to activate Final Hour

this mastereis tree of mastery is not my... in real im using a masteries tree of jhoijhoi