Not Updated For Current Season
The masteries shown here are not yet updated for the current season, the guide author needs to set up the new masteries. As such, they will be different than the masteries you see in-game.
So I used to play Ezreal a ton back in the day before he got nerfed and what not and stopped once he was hit. I have however begun to play him alot more because I seem to have found a build that works quite well with him. Its a hybrid build believe it or not and I have great success when using it.
I start out with a Meki Pendant and two Health pots. Going mid as Ezreal is always the best option because he is excellent at farming and at poking. Get your Q leveled first and use it to farm and poke, mainly to farm. Between your Meki Pendant and Mana Regen runes you shouldn't be have any mana problems unless you spam your skills every possible second which would just be wasting them. Basically just try to farm to your best skill possible. Use your ult to try and snipe side lanes, you'd be surprised at how fun and useful it is once you get good at sniping with it. Get your build up, once you hit the boots, archangel and madred's blood you'll be dishing out some nice damage from your abilities and auto-attacks.
Has great poking skills
Great Damage output
Awesome ult (One of my favorites)
One of the best dances in the game
Needs items to be affect
If you are bad with skillshots he isn't the champ for you
Basically Ezreal is all about the skillshot. Three out of his four abilities are skillshots and even the one that isn't is a bit tricky to use. I would put him under the more difficult to use section of champs because he is very squishy and uses skillshots. Once you get the feel for him however, he is extremely fun to play and has a ton of damage output.
This isn't one of those huge in depth guides. I just wanted to show everyone how I built a champ because it seems to work very well. Work on those skillshots, stay clear of mobs and sit back and have fun wrecking people from a distance. Ez is extremely fun to play and requires alot of focus and attention to properly land hits, escape, chase ect. I hope you have the success I have had with this build and with Ezreal. Happy LoL'ing to everyone.