INSTAKILL ADC IN 2 AUTOS
Threats to Vayne with this build
How to play with Thunderlords
At first laning phase will be difficult depending on who it is but lets say for example you go against a Sivir,You should try to make sure you can burn your thunderlords because she cannot spellshield it all you need to do is 3 autos or auto Q and E. that will be the basic combo and if you can try to fight at level 6 and hide in bushes because if you have Duskblade if you are unseen for 1 Second you will do extra true damage then magic damage because of your masteries if you stay in a bush and then ULT Q out the kill the enemy.
If you are not doing so well in laning phase due to having thunderlords Try to make sure you play safe if you see a good opportunity for trade then go for it and if you have your jungler around try to initate the fight after OR if the enemy adc or support is near a wall auto condem them and then Q after to get the thunderlords Proc off and if your jungler is there try to make sure you dont get low enough to die or let your support engage for you and then use your ultimate in messy spots
Tips for Vayne
When there is a fight in the mid lane lets say and the adc is out in the open and you think you can kill him wait in a bush if there is and then R Q outside the bush so he cant see if he gets close enough you will usually win the trade if you are not suepr behind