This build is very strong in DMG and will kepp you alive and going in even 1v3s. I focus mainly on the on-hit effecs and DMG because Warwick relies on his auto attack as his main source of DMG. Items like Madreds Bloodrazors and Wits End are very important to Warwick because of those on-hit effects. This is my very first build, constructive critism and comments would be greatly appriciated.

PROS
Amazing ganker
Great survivability
A very good chaser due to blood scent
Best ingame jungler

CONS
Very susceptible to early game counterjungle/ganks
Very mana reliant
Leaves a a teammate in a 1v2 situation
Team dependent

I go with a 21-0-9 because i play Warwick as a dps champion. I pick up the improved smite and the extra magic pen. but besides that its the normal 21-0-9.

Another option is the 0-21-9, this will give you a little more armour, health, and bulkyness in the beginning but the jungling route wont be to intense, so i dont recommend this but it is an option none the less.

These items are very strong on Warwick because he relies on hit effects (Bloodrazor, Malady, Wits End Ect...). The only item I feel i should explain is the Hextech Gunblade. I picked this item because it gives major bonuses it provides Warwick. The lifesteal for obvious reasons, the spell vamp for his bite, the DMG for ult and auto attack, the AP because his bite scales AP, and the Passive Bonus of the item (slow and 600 DMG). It may be substituted for a Bloodthirster, but i believe this to be a better choice.

I go with flat DMG runes marks and Quints (Reds and Bronze), armour seals (Yellows), and attack speed glyphs (Blues) for the sheer hitting power, speed, and survivability in the jugle/laning phase in the beginning. You could substitute the glyphs for mana/sec for even longer jungle/laning duration but I feel they arent neccasary when your getting the Blue Golem almost every chance it spawns.

I use a R,W,Q repeat combo. This combo is for more of a 1v1 situation because it imobilizes one champion and it focuses on mainly the high burst from ult and sustaned power from the W. Another combo I use is a Q,W,R this is more of a team fight because if you get targeted in the middle you can easily flash out, but if you kill the enemy with your ult it can just serve as a killing blow and you may still flash out.

I picked Smite for one very obvious reason, for speed jungling. Speed in the jungle is key to picking up the quick levels and buffs so you may quickly overpower your enemies.

And secondly I picked Flash. Flash is by far the best summoner spell because of its many uses. You can flash to get away from enemies, to engage, to set up ganks, ect...

Ghost is also a viable option as well as exhaust. I say this because in the beginning your blood scent will speed you up but not a significant amount, it will allow you to catch up with them but not use many auto attacks. Ghost and Exhaust can keep you with them so you can keep hitting them and keep bringing them down.

Ok, so my Warwick Technique is a little odd. I call it periodical jungling because you spend only about 20 percent of your time in the jungle.
The Order- The 2 small golems, lane, when they spawn grab them again, lane more, grab the blue and then the red, and from there on lane and grab any buff on your side of the map anytime it comes up. I do this to get the extra XP from the jungle creeps. As your laning you are sharing XP with another player, but when you jungle you are getting the solo XP. When you are getting the jungle solo XP your teammate is also getting the solo XP, so its very beneficial for you and your teammate.

Ganking is one of Warwicks strongest attributes. ALWAYS gank when the oppurtunity presents itself, the extra gold and kill/assist is very good for you and your teammate.

Ult Usage- Warwicks ultimate can be used as a initiator and a finisher. I personally use it when I engage an opponent so i can get them into low health ASAP to activate blood scent. The other choice is to finish with it, you can auto attack and bite to get them around half health and then use your ult so they put you into blood scent. Chase them and easly net yourself a kill.

There are a few key things i always do when i play Warwick, the first being i stay completely passive until level 6. (Excluding the times when your teammate engages and there is a chance you might net a kill.) Another is that if someone comes into turret range have your ult ready to be casted because if they take turret aggro even once you can suppres them in the range and easily pick them off and gain a kill.

This build will hopefully help you become a better Warwick player, and give you those higher scores that everyone looks for. As i said before this is my first build and i would greatly appriacate help,tips, and advice. Thanks.