Karma Build Guide by
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Karma deals incredible damage with her Heavenly Wave, which also will heal your teammates as you active Mantra before Heavenly Wave. Using Mantra > Sould Shield will give your teammate(s) incredible much bonus health for a short delay, also dealing insane damage to your enemies. Slowing them down with Spirit Bond OR giving your team extra movement speed is a bonus for easier kills.
Using her Heavenly Wave first > Then Mantra and Soul Shield would take all the creeps down > Giving Karma a incredible farm in late-game.
Using Flash and Ignite: As Karma mid, enemies will get really aggressive against you as they think Karma is really bad, because she is a support. But of course, they are wrong. Karma deals incredible damage to ANY other AP carry's, and would win the lane really easy. The flash is really usefull against ganks, also ignite would save her some kills as she got cooldown on spells.
Using Sprint and Teleport: Sprint would be great to catch up a target to slow enemies movement speed down as your team can kill the target. Teleporting to a ward in their jungle\bush on any lanes would be a easy pick-up kill.