Not Updated For Current Season
The masteries shown here are not yet updated for the current season, the guide author needs to set up the new masteries. As such, they will be different than the masteries you see in-game.
This build for Kayle is meant for an end-game player since the items take a long amount of time to farm gold for. But once Kayle is Level 18 with this complete set she will have no problem taking on 4 opponents at the same time, soloing turrets, and taking out half of the Baron's health.
I personally don't use runes yet but this is what I would hope to be a good rune guide for this build.
Pros / Cons
Great tanker: She can kill enemies in a matter of seconds
Insane PK: Kayle does more than 500 damage on opponents with crit damage on basically every attack.
Life Leeching: With a crazy amount of attack speed, Kayle is able to life leech with almost every attack.
Movement: This build brings Kayle's speed to her limits and allows her to speed through terrain as well as rush to the aid of her team and their base.
No armor: This build requires that Kayle doesn't purchase any armor increasing items. This makes it hard for her to withstand too many attacks.