Pantheon is a damage based character for me, although some people (noobs) think he should be tank if you are one of them leave this build now. He has a gigantic damage burst and global teleport. Keep in mind that this build is for late game monster

I use Greater Mark of Desolation because when you play against armored characters it can be very usefull. As for the other focus runes it can save you alot of times because of his burst damage he is only afected by cooldowns

I have nothing to explain you will need critical strike chance and armor penetration for the obvious reasons

first you will need long sword for spell damage because as you probably know pantheon uses atack damage to make his spells deal more damage. You will need boots of swiftness because for Atack / Defense because you will be faster than most players and you will be able to run away easily catch up to a wounded enemy faster. The brutalizer is just for early/mid game in late game you can replace it with an item of your choice depending on the situation. You will need Sword of the Occuit because with all the assist and kills you will get you will easily round up more than 50 damage for it. Phantom Dancer is the next thing you will need because you will move/atack faster and crit alot often than normal. Infinity Edge will be needed for damage more critical strike. And last but not least the blood therster will be for more damage and lifesteal. if you have ennough gold you can replace the bruthalizer with another bloodthirster

1.Spear shot (except if you are not rushing for FB) 2.Aegis of Zonya (it will save youre live and help you and your teammates to kill an enemy 3.Heartseeker strike (at this moment you will be a killing machine and easily kill enemies with less than 50%health 4&5.heartseeker strike (at this moment we want to make you more damaging to your opponents 6.Grand Skyfall (for the obvious reasons of global teleport) everything else is depending on the case but please stick to the build if you can.

Clarity: Because Pantheon is really mana hungry early/mid game it can be really bad if your mana runs out in battle so this will be a savior in some cases
Ignite: If you have ever played with Pantheon you will know the bad feeling of leeving an opponent at 100-200 health so this spell will make the bad feeling go away

So if you want to prosper with pantheon pls follow this guide
Credits for the guide go to DIMCHOBG from the Europe server