How to f*ck up the enemy ADC
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Not Updated For Current Season
The masteries shown here are not yet updated for the current season, the guide author needs to set up the new masteries. As such, they will be different than the masteries you see in-game.
How to do the One-Shot
First of all you need to get at least everything except Infinity Edge (And of course lvl 6).
Also you have to be a little bit fed and you need to choose a squishy victim to One-Shot.
Then go and get full Ferocity. After that find your victim, activate your Ultimate and Youmuus and get ner him. Now the tricky part:
1. press Q (full Ferocity)
2. Jump on victim
3. Use E in Mid-Air (While you are jumping on him)
4. When you land on victim, use W and Hydra at the same time.
5. Your victim might be dead now, but if not, you will have full Ferocity like 1 second after your combo and you can use Ferocity Q or Ferocity E (stun) to finish him.