Not Updated For Current Season
The masteries shown here are not yet updated for the current season, the guide author needs to set up the new masteries. As such, they will be different than the masteries you see in-game.
Well, i made this guide to help one friend that was using AP on ryze and loosing all the games, as i plyed ryze several times when he wasnt a mana user but a AP user it was good, but now ryze is only mana, and its better becouse there are several items with mana and resists and health too.
My runes explanation is: more mana more dmg, more regen = harassment with Q, and more hp = more time in lane, easy.
This is my custom items, when the enemy team have 1 tank, 2 Ap and 2 AD, if they dont have AD dont build armor, if they dont have AP its different, u should build the banshees veil if they have a lot of cc, and then build armor.
Well, this is the fun part, with ryze u can just harass then before the team fight begins, ur Q now have LOW CD and with ur passive u can just spam it, and with the mana build u will never have mana problems, I almost always do a good score with ryze if I dont engage before tank, that sometimes i cant do :P
well i know its a weak explanation about the build but theres not much to say about it, if u want to know anything about how i play just post something.