The newly buffed Ryze is actually worth playing now. Though he lacks a stun, his single-target burst damage is amazing but so is his AoE burst damage due to his ult. Be careful, though; this item build will make Veigar destroy you.
Great single-target nuke. Pretty short range, so be careful not to suicide with it when you're trying to grief with it.
Ryze's only CC, so it's his main skill. Single-target instant snare. Be careful with its short range.
Ryze's longest range spell. Pretty unreliable for killing someone when there's lots of other enemies near them, so don't expect much. It can bounce off of Ryze, so don't worry if your target is alone.
Instant-cast 0 mana AP buff that makes Ryze's spells deal AoE damage.