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Diana
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S4 Mid Lane Diana
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Thanks for the vote! When I think of Nashor's Tooth on Diana I compare it almost to buying it on champions like Twisted Fate or Orianna. Yes the DPS may end up being very high but there's so much more potential for damage in your other spells, especially when your trying to take down targets as quickly as possible. If you just stack AP you'll take down targets incredibly quickly and do tons of AOE damage, which is what we want for Diana. Besides, Diana can still get incredibly large amounts of damage out of her passive. The passive attack speed makes it easier to utilize, and the buff to the AP Ratio made it a strong source of damage even without DPS items like Nashor's Tooth.
By all means buy it if you have success with it but I find it out classed and unnecessary.