Sejuani is a strong tank who does a lot of slow. She is a great choice, especially in Ranked Games, because her slows and stuns are very helpful for her teammates.

Taking these runes will make Sejuani a real tank that is hard to defeat. If wou would like to change them or have other runes, some attack damage would be good.

With these masteries, Sejuani will be more tanky and tougher. But, if you would like to play her in jungle, masteries should be changed to 0-21-9.

These items allow Sejuani to do more slow than ever. It combines armor, magic resistance and health with attack damage and ability power. Instead of Guardian's Anger, you can build Warmog's Armor.

This skill sequence is not random. Maximizing Permafrost (E) will help Sejuani, if played with an other teammate and not solo, and her teammate to take first blood quickier or even a double kill.

The summoner spells are very significant. With flash, you will be able to escape or initate team fights and with exhaust you will lower one's resistances, allowing you and others to kill them faster. Instead of exhaust, you can take cleanse or heal.

To sum up, playing Sejauni hybrid, tanky and dps, will help your team more than ever before!