Not Updated For Current Season
The masteries shown here are not yet updated for the current season, the guide author needs to set up the new masteries. As such, they will be different than the masteries you see in-game.
Early Game: Harass as much as possible. Void ooze has great range, so you wont have to get too close to hit them. as soon as you hit lvl 2 make sure to take advantage of bioarcane barrage. Always make sure you last hit minions, so you can get the chalice and boots as soon as pissible.
Mid Game: As soon as you hit lvl 6, you should be doninating the harass game. You will be able to pick off weak enemies on the gank as well. Make sure to support your team, and if they are fighting make it your goal to hit the enemy with living artillery as it will boost their slayiing ability, and give them a decent edge.
Late Game: Make sure to get all your items, you are very item dependant. Make sure to take full advantage of the living artilleries very short cooldown. Aim to hit the enemy with living artillery, then void ooze, and activate bio-arcane barrage. you will take down the enemies health in a matter of seconds with the auto attack, and hit them with living artillery as they run. You will rack up kills in no time.