Not Updated For Current Season
The masteries shown here are not yet updated for the current season, the guide author needs to set up the new masteries. As such, they will be different than the masteries you see in-game.
Twitch - The Plague Rat
This is my version of a few Twitch builds smashed into a beastly combination. You will be spitting out arrows faster than ever while punishing the enemy with massive damage along with critical damage. This is also my first build so please comment nicely and help me improve!
Great carry, can annihilate teams in a matter of seconds.
Is a great crippler
Can scout for your team
Can escape with Ambush
Squishy, easily killed
Can be CC'ed
Since you are a carry, everyone will be out to get you
Oracle's and wards can stop you from scouting, and escaping with Ambush
Greater Seal of Alacrity
This seal is great for twitch, adding godly amounts of attack speed.
Greater Mark of Desolation
When that fat tank charges for you with a massive amount of armor, do not worry Mark of Desolation is a killer!
Greater Glyph of Malice
Lovely glyph to increase your critical chance, which will help with your critical damage obviously!
Greater Quintessence of Desolation
Great for more armor penetration.
I like using Cleanse with Twitch because he can removes slows for quick escapes(especially when they got wards or oracles).
Okay, now most of you probably disagree with the heal. Honestly I need it!!! I have to still learn my limits and often go into bad situations. !!!!-YOUR CHOICE-!!!!
Starting off with the Vampiric Scepter is good idea because, Twitch is squishy early game so the early life steal helps you out and gets you more money(not having to go heal).
Getting these boots gives you a extra boost of defense helping your low life champion.
Okay now personally I love getting this for Twitch. It gives you great attack speed and armor penetration. What a deadly combo!
Now to start working your damage! This sword gives you nice damage and improves your critical chance.
Woohoo even more attack speed and critical chance! This time you even get some dodge and movement speed.
The Black Cleaver
To bring more damage to the plate, This bad boy gives you plenty damage and reduces your enemy's defense by 12, for every physical attack lasting 5 seconds.(Also stacks up to 5)
This monster gives you 100damage. Also gives you 25% lifesteal! Lastly for every kill it gives an additional 1 Physical damage and 0.25% lifesteal. (maximum +40 damage, 10% lifesteal)-->Bonuses lost at death!
Now I have some changes I do toward end game!
Ninja Tabi, for extra damage and attack speed while keeping the +25 armor from ninja tabi.
The Black Cleaver, this switch gives you 15HP per 5 sec but mainly do the switch for the splash damage! But yes you do lose 32 damage.
I hope you found this guide helpful and please comment for improvements, typos, etc.
p.s. please if you do view it try it out and score it, I would like to get this on the list of good guides!