Not Updated For Current Season
The masteries shown here are not yet updated for the current season, the guide author needs to set up the new masteries. As such, they will be different than the masteries you see in-game.
Who like play squishy and strong characters, this build it's for him. Twitch in my build have only 2450 hp but his dmg and life stall allow him to win with all. He has problems onlwy with magicians bc for example veigar's combo can kill him in 2 sec, but your hits inflict avarge 300-500 dmg. So if you apply element of suprise you can win with all