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This is the final version of the build I have been using to level up playing as Twitch. It is all about attack speed. I am currently not using the runes for Attack damage, due to needing the attack speed early on. By the time you have malady, and the phantom dancer, you will be using stealth more for the bonus than anything. Even though you can do some massive damage, especially with your ultimate, Twitch still has low survivability. You must play to your advantage, fight when the time is perfect, wait for their life to lower before striking. Now, I am not saying be selfish and just let the Team die, but if done right, you will have very minimal deaths.