Not Updated For Current Season
The masteries shown here are not yet updated for the current season, the guide author needs to set up the new masteries. As such, they will be different than the masteries you see in-game.
twitch is a very powerful dps. twitch get extra attackspeed from hes spells, so many attackspeed items is'nt a very good thing for twitch. however damage and crit change is very good! if you wanna play twitch as a ambusher (stealth around in all map and kill from behind) then it will be a good thing to buy boots og mobility to get fast around in map. if someone from the other team buy orakle or set up wards to see invisible, then you have to change lane with a team mate, because twitch is bad when he cant stralth around. when you will ambush as twitch, then you need a mate to attack first, because if twitch got low hp and armor, so he can almost be one-shoted from some champions. when you go to attack, and a champion run away, then remember how much posion he got on, so dont tower-dive if posion is powerful enough to kill him. remember twitch got low hp and armor, so if you got half hp, its dangerouse to keep killing.