ADC Varus season 6
Not Updated For Current Season
The masteries shown here are not yet updated for the current season, the guide author needs to set up the new masteries. As such, they will be different than the masteries you see in-game.
With this build, what you want to do first is try to rush bloodthirster and berserker's greaves. After that, just continue the build in that order
As Varus does not have any escapes, try to predict when you are in danger, so you can use E to slow, and if it gets really dangerous, then use R and run away and flash if needed.