Vayne ADC (6.14)
Full Build vs Heavy AD
Full Build vs Heavy AP
Full Build vs Tanks
Not Updated For Current Season
The masteries shown here are not yet updated for the current season, the guide author needs to set up the new masteries. As such, they will be different than the masteries you see in-game.
Play as passive as possible. Only go for kills when support creates chances or enemy makes mistakes. Use silver bolts passive to farm. Take all 3 shots on minions for easy last hit Do this till roughly level 8 or 9.
Try to stay in lane to farm and push as much as possible excluding team fights and objectives. eg. Taking turrets or Drakes and Rift Herald. Now take kill opportunities in lane as much as possible to get fed early for late game. If the enemy makes a mistake immediately take the opportunity.
Continue to push your lane out and take advantage of other winning lanes. Make sure you stay with a teammate (preferably your support) at all times. And make sure to be involved in the back line of every teamfight. You can use your ultimate to engage a fight by ulting and tumbling before engaging. But try and wait for a more tanky player to engage before you use your ultimate. It is your job to focus as much of your damage as possible onto the enemy carries like ADC's and Midlaners. Basically anyone that deals a lot of damage is your priority. Dont focus tanks or utility players.