Not Updated For Current Season
The masteries shown here are not yet updated for the current season, the guide author needs to set up the new masteries. As such, they will be different than the masteries you see in-game.
Threats to Vayne with this build
|Sivir||Sivir is a team-based ADC. While she isn't dangerous in lane, you can play agressive against her. It's important to dodge her Boomerang (Q) so you can easily win nearly every trade.|