13.5.2011 -- guide created.
14.5.2011 -- added short summoner spells section.

Hello this is my 3rd guide on Mobafire!
I am from LoL eu and im around 1200 elo 5v5 solo queu.
I play vayne as crit dps because she can 3 hit carries and even bruisers when full build.

Pros
-very good harasser
-can do great damage all trough the game
-insane true damage
-good chaser
-very mobile

Cons
-very squishy
-item dependant mid/late game
-gets focused down

Vaynes passive It increases your movement speed when running towards enemies.
Its usefull also for checking if there is enemies in bushes waiting for gank.
just go so that you can see the bush and turn towards it if the particle effect launches there is someone.

This ability is your bread and butter. you should use this frequently in fights ganks etc.
it good also for kiting, escaping and chasing. NOTE! It cant go over walls.

This ability does true damage based on targets max health on 3rd hit is also counted as hit. this ability can shred your opponents health in seconds thats why we roll also AS.

This ability is great at the beginning to gain fb also its good to towerdive enemies.

This ability is one of the best ultis in the game. you can easily assasinate enemies with it before they even realise it and you can also escape pretty well with it.

Is almost a must as first item! it gives you hp which you need at start + damage and lil lifesteal. Is a good choice for boots but ionian boots of ludicity Is better choice since it gives much CDR
Which boosts your but both are legit.
Crit AS and Movement speed what can I say? Perfect item for crit Vayne. The movement speed makes you very crazy chaser.
This is a must! If you get this early enough you can 3x crit kill opposite teams squishys. you must get this before boots because you dont need boots that much early game and it gives your awesome buff!
You will need this item before upgrading to since you cant really stay alive in teamfights at this point without it. The stats this item gives are all great for you (expect AP) and it gives 50% more damage after using ability than . Last item is very situtational against armor stackers against tanks and offtanks or if either of the other wont fit.

Sidelane
EARLY GAME
Grab dorans blade and head to bot lane. take as first skill and when they intiate for fb
go quickly to their side and stun one of them at the wall. This normally gives you certain fb.
Start farming some minions try to last hit them and dont push too hard. Get next. Try to harass your enemies by tumbling at them and shooting once then retreat.
when you have you can try for easy kill. tumble at them and stun them at wall if possible tumble again and then just autoattack and that just do the job.
when you are level 6 gank mid lane it should be very easy at this moment.

MID GAME

Now your job is to gank every lane where there is opponents. Be sure to grab the buffs every time possible. Dont intiate team fights, you should be last to go in.
your combo should be next --> autoattack --> --> --> autoattack--> --> autoattack

this Combo should kill anyone if you have and .

LATE GAME

At this point there will be most teamfights. You should go last to them and focus on the offtanks/tanks.
remember to push lanes since you are ad carry.

I like most the and combo.
Its good since it gives you great movement speed synced with your passive and good last hitting skill for runners.
but other legit combinations are...
and
This gives you more survivability.
and
This combo gives you more chasing and escaping power.

remember to change your masteries to best suit your summoner spells.

The game lasted for like hour and I carried our whole team as you can see!
It was very equal match we had 0 towers and so on.