ok so every1 says vayne has the worst early game ever but with these runes just keep applying your w over and over you can force them out of lane... yes forcing ppl as vayne.

Mid game is simple you should have ie ghostblade boots or bloodthirster yes atleast three items
mid game if your'e still in laning just css and fight them whenever.if your'e not in laning phase roam and help other lanes with three of these items u can fight most ppl.

late game is fun when u have all the items infinite edge,ghostblade,bloodthirster/phantomdancer ,phantomdancer,last whisper.you can run around and kill ppl in 3 or 2 shots you have 100% crit how is this not fun