Not Updated For Current Season
The masteries shown here are not yet updated for the current season, the guide author needs to set up the new masteries. As such, they will be different than the masteries you see in-game.
Threats to Vayne with this build
|Kalista||Low damage and the kite passive doesn't help her as much as it would with other champions due to your passive movespeed and kite of your own. Be careful in 2v2 for her passive procs and be mindful of her stacks on you and you will be fine.|
|Twitch||Low damage, low impact, not much to bring to the table. Play safe when you see him go into stealth or you think he's not there.|