Not Updated For Current Season
The masteries shown here are not yet updated for the current season, the guide author needs to set up the new masteries. As such, they will be different than the masteries you see in-game.
This is my first Guide so bear with me here.
Vladimir has incredible damage output and with the right amount of survivability he rarely has to leave the battlefield. This builds biggest plus is the power to take down the big baddies.
I start off with a Amplifying Tome and a health pot.
On second visit try to pick up boots of speed +1 and upgrade your tome to hextech revolver, the additional lifesteal helps a ****ton in sustainability.
quickly work towards the sorcerers boots.
Afterwards get your hands on a Rylai's scepter, this is where youll be doing some serious hurt. you should be round midgame here and with maxed out transfusion you can harass ******edly.
next thing to work on is haunting guise, at this point the enemies base magic resist will be hurting pretty bad here.
Adding a zhonya's ring should set you up pretty nicely. And to make it nicer upgrade your hextech to a will of the ancients- now with your ult you are your teams best friend. now the only thing that could help you destroy things more is more life- i personally go with a randiuns omen- however warmogs is a great alternative as well as a sunfire cape if youre just destroying. the omen helps greatly with getting away.
If the game happens to still be going on then id switch out haunting guise for abyssal scepter for even more help teamwork wise.
As long as you dont initiate end game you will lay some serious hurt on the enemy.