Welcome to Zurfarii's Twitch Guide!
I am a Platinum Player on EUWest Server, my IGN is FrostedCupquake . I play ADC whenever I can in ranked, and to great success. My stats are at the bottom This Guide is for anyone looking for what to build on twitch, learning how to play him, or just want to see if there is any aspect on which they can improve on. Twitch in my opinion is the strongest ADC at the moment, (12.08.2013) With his brilliant harass and poke, aoe damage, burst potential and dueling skills! If you want triples, quadras, pentas then look no further than this guide! =)

If you disagree or have any improvements, please email me zurfari1@gmail.com

This is my first guide so please check it out and help me if possible!

Pros
Has IMO 3rd best late game as an ADC
really good range on abilities (His ult outranges turrets FFS!)
Has a decent slow to stop people escaping, and a poison to finish them off
An ultimate that hits everyone near to your target in a fight, stacking them and doing a ****tonne of damage!
Twitch is a high skillcap champion, being good at him will make you a better player.
Top 3 ADC for dueling

Cons
Only CC he has is a slow
Positioning is everything is twitch, if you are out of position, you are dead.
No instant get away, takes time to use his stealth
Needs other aoe CC to make him fully effective
Heavily dependent on a support to make plays for him.
He smells quite a bit and is the second ugliest ADC to urgot xD

Marks:
Flat Attack damage is really the way to go. As with most AD carries, attack damage/level ( Greater Mark of Scaling Attack Damage) and attack speed runes ( Greater Mark of Attack Speed) just don't quite do the same damage.
Seals:
Because you are twitch, and you already have ungodly low amounts of armor and Magic resist, I Strongly suggest you use Greater Seal of Armor for armor.
Glpyhs:
In addition to having low armor, Twitch also has really low magic resist. Twitch has enough trouble surviving already! Getting Greater Glyph of Scaling Magic Resist gives twitch more sustainability against those pesky AP champions!
Greater Glyph of Magic Resist is a fine alternative as well.
Quintessences:
Greater Quintessence of Attack Damage Yields a strong early game damage boost. You can capitalize on this to increase the damage from your expunge, and harass, gank potential, and farm capabilities.
Running Greater Quintessence of Life Steal yields an early game advantage, but in a different sort of way. Running 2 of these quintessences allows for faster recovery of hitpoints after trades. With this in mind, these quintessences are best for twitch when he has a poke support that likes to trade often. While these quintessences limit your burst capabilities early game, they make it easier to stay in lane, and force your opposing lane to recall more often.