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Cassiopeia Build Guides, Runes and Items

Cassiopeia The Serpent's Embrace

Find the best Cassiopeia build guides for League of Legends S14 Patch 14.6. The MOBAFire community works hard to keep their LoL builds and guides updated, and will help you craft the best Cassiopeia build for the S14 meta. Learn more about Cassiopeia's abilities, skins, or even ask your own questions to the community!

Season 10 Builds
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

S10 Cassio ultimate build

Build by puni297 updated January 6, 2020
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

S10 Cassio ultimate build

Build by puni297 updated January 6, 2020
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassiopeia Best Runes/Build Season 10

Build by CassiMAIN updated December 27, 2019
7.9
15
Votes
4
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Aniki's Conqueror Cassiopeia Guide

Build by AnikiTaka updated December 9, 2019
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Season 10 Cassiopeia Runes and Build

Build by SawyerNelson updated December 10, 2019
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Ultimate Cassiopeia Mid's Guide

Build by Shyokapik updated December 7, 2019
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

cassiopeia

Build by XD Crabby updated December 6, 2019
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

CASSIO

Build by Canc3RS updated December 9, 2019
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassiopeia conqueror

Build by maxyx21 updated December 2, 2019
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Kalista

Build by Guest updated November 29, 2019
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Aniki's Cassiopeia Guide

Build by Guest updated November 25, 2019
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Ultimate Cassiopeia Mid's Guide

Build by Guest updated November 24, 2019
Season 9 Guides
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Bruiser Cass Carry

Guide by 0n1yg4m354nd1if3 updated September 4, 2019
10
481
Votes
26
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

In-Depth Competitive Cassiopeia Guide - With Comet Cassio!

Guide by Xavier Senori updated August 10, 2019
  • In-depth
9.7
27
Votes
1
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

How to play Cassio from early to late (climbing, comet cassi

Guide by Romusracker updated December 19, 2018
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassiopeia Mid 8.23

Guide by BattleXD updated November 24, 2018
Season 9 Builds
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

speed casi

Build by Guest updated October 17, 2019
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassio Guide

Build by Draughlox updated September 16, 2019
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

BEST ADC CASSIOPEIA BUILD

Build by EZZZOO updated August 30, 2019
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

mine

Build by Guest updated September 6, 2019
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Cassiopeia Build & Runes

If you're looking for the best rune build for Cassiopeia we've got you covered. Below you can find the best items and runes to build for Cassiopeia, as determined by calculations of thousands of Plat+ League of Legends games. If you are already familiar with how to play Cassiopeia this is a great resource to quickly get a good rune selection for Patch 14.6. However, if you are a new Cassiopeia player we highly recommend reading through some of the guides above to learn why this build is strong on Cassiopeia!

Our Stats Powered By LeagueOfGraphs.com LogoOpen In New Window
Patch 14.6: 25,957 matches scanned * Each section of the build is rated independently of the others

Cassiopeia's Runes

Cassiopeia's Best Runes 51%

Win Rate 66% Pickrate

  • 1
  • 2
  • 3
Precision
LoL Path: Precision
LoL Rune:
LoL Rune:
LoL Rune:
LoL Rune:

Sorcery
LoL Path: Sorcery
LoL Rune:
LoL Rune:

Second Best

Cassiopeia's 2nd Best Runes 50%

Win Rate 16% Pickrate

Sorcery
LoL Path: Sorcery
LoL Rune:
LoL Rune:
LoL Rune:
LoL Rune:

Precision
LoL Path: Precision
LoL Rune:
LoL Rune:

Third Best

Cassiopeia's 3rd Best Runes 51%

Win Rate 13% Pickrate

Precision
LoL Path: Precision
LoL Rune:
LoL Rune:
LoL Rune:
LoL Rune:

Resolve
LoL Path: Resolve
LoL Rune:
LoL Rune:

Cassiopeia's Summoner Spells

Cassiopeia's Best Summoner Spells 51%

Win Rate 75% Pickrate

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Summoner Spells 51%

Win Rate 12% Pickrate

Flash Ghost

Third Best

Cassiopeia's 3rd Best Summoner Spells 48%

Win Rate 6% Pickrate

Flash Ignite

Cassiopeia's Starters

Cassiopeia's Best Starter Items 50%

Win Rate 79% Pickrate

  • 1
  • 2
  • 3

Cassiopeia's Core Items

Cassiopeia's Best Core Items 54%

Win Rate 20% Pickrate

  • 1
  • 2
  • 3

Cassiopeia's Ability Order

Cassiopeia's Best Ability Order 50%

Win Rate 57% Pickrate

  • 1
  • 2
  • 3
Our Stats Powered By LeagueOfGraphs.com LogoOpen In New Window
Patch 14.6: 25,957 matches scanned * Each section of the build is rated independently of the others

Cassiopeia's Runes

Cassiopeia's Best Runes 51%

Win Rate 66% Pickrate

  • 1
  • 2
  • 3
Precision
LoL Path: Precision
LoL Rune:
LoL Rune:
LoL Rune:
LoL Rune:

Sorcery
LoL Path: Sorcery
LoL Rune:
LoL Rune:

Second Best

Cassiopeia's 2nd Best Runes 54%

Win Rate 25% Pickrate

Sorcery
LoL Path: Sorcery
LoL Rune:
LoL Rune:
LoL Rune:
LoL Rune:

Precision
LoL Path: Precision
LoL Rune:
LoL Rune:

Third Best

Cassiopeia's 3rd Best Runes 52%

Win Rate 5% Pickrate

Precision
LoL Path: Precision
LoL Rune:
LoL Rune:
LoL Rune:
LoL Rune:

Resolve
LoL Path: Resolve
LoL Rune:
LoL Rune:

Cassiopeia's Summoner Spells

Cassiopeia's Best Summoner Spells 52%

Win Rate 85% Pickrate

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Summoner Spells 48%

Win Rate 7% Pickrate

Flash Ghost

Third Best

Cassiopeia's 3rd Best Summoner Spells 52%

Win Rate 5% Pickrate

Flash Ignite

Cassiopeia's Starters

Cassiopeia's Best Starter Items 52%

Win Rate 72% Pickrate

  • 1
  • 2
  • 3

Cassiopeia's Core Items

Cassiopeia's Best Core Items 56%

Win Rate 14% Pickrate

  • 1
  • 2
  • 3

Cassiopeia's Ability Order

Cassiopeia's Best Ability Order 50%

Win Rate 44% Pickrate

  • 1
  • 2
  • 3
Our Stats Powered By LeagueOfGraphs.com LogoOpen In New Window
Patch 14.6: 25,957 matches scanned * Each section of the build is rated independently of the others

Cassiopeia's Runes

Cassiopeia's Best Runes 51%

Win Rate 60% Pickrate

  • 1
  • 2
  • 3
Precision
LoL Path: Precision
LoL Rune:
LoL Rune:
LoL Rune:
LoL Rune:

Sorcery
LoL Path: Sorcery
LoL Rune:
LoL Rune:

Second Best

Cassiopeia's 2nd Best Runes 53%

Win Rate 13% Pickrate

Precision
LoL Path: Precision
LoL Rune:
LoL Rune:
LoL Rune:
LoL Rune:

Inspiration
LoL Path: Inspiration
LoL Rune:
LoL Rune:

Third Best

Cassiopeia's 3rd Best Runes 57%

Win Rate 12% Pickrate

Sorcery
LoL Path: Sorcery
LoL Rune:
LoL Rune:
LoL Rune:
LoL Rune:

Precision
LoL Path: Precision
LoL Rune:
LoL Rune:

Cassiopeia's Summoner Spells

Cassiopeia's Best Summoner Spells 52%

Win Rate 49% Pickrate

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Summoner Spells 54%

Win Rate 19% Pickrate

Flash Teleport

Third Best

Cassiopeia's 3rd Best Summoner Spells 48%

Win Rate 12% Pickrate

Exhaust Flash

Cassiopeia's Starters

Cassiopeia's Best Starter Items 54%

Win Rate 79% Pickrate

  • 1
  • 2
  • 3

Cassiopeia's Core Items

Cassiopeia's Best Core Items 51%

Win Rate 10% Pickrate

  • 1
  • 2
  • 3

Cassiopeia's Ability Order

Cassiopeia's Best Ability Order 50%

Win Rate 53% Pickrate

  • 1
  • 2
  • 3

Cassiopeia Counters

Learn Cassiopeia's counters and discover matchups where they have an advantage! When you're starting a game of League of Legends you should always keep in mind if you'll be at an advantage or disadvantage against your opponent, so you can know whether to bully them or play safe. You can find detailed breakdowns of each matchup on CounterStats, and you can also check out some Cassiopeia guides to see how to build and play against other champions you may find yourself up against!


This counter data is for Cassiopeia MIDDLE in Plat+ games. The percent shown is the enemy champion's counter rating against Cassiopeia. Counter rating is our own statistic that factors in counter kills, overall kills, early lead ratio, comeback ratio, and win percent to give the whole picture of that champion's effectiveness as a counter pick.

Cassiopeia Skins

Cassiopeia's Abilities

Questions About Cassiopeia

Ask

Latest Questions

Feeling difficult to deal damage to mages who build RoA, what should I do?

Situation: In the early-mid game, I built Morellonomicon, opponent built RoA. Problem: Feeling difficult to deal damage to opponents who build RoA. As they have higher effective health after building RoA, I feel like 'my abilities do not...

View (4) Answers

Which way is Katarina facing when she ults?

If you need the enemy to be facing you for the Cassiopoia ult to be a stun, then which way is Katarina facing while she is ulting?

View (2) Answers

Question on Cassiopeia

I want to main Cassiopeia mid to climb the ladder, but i'm far from learning anything about her besides some combos. Should I just focus on tear for the majority of early, or is it better to constantly harass my opponent? What match-ups do I...

View (2) Answers

Who should i choose?

???????????????????????? [b]Best Option[/b] ???????????????????????????????????????????? [color=#0080ff]Ahri , Cassiopeia , Diana , Ekko , Vladimir[/color]

View (3) Answers

Who is the most OP champion in the game?

I am wondering who is the most OP champion to play. I wanna see how well I can do.

View (23) Answers

What are some fun or brainless champions?

I have no idea who I should buy; any suggestions?

View (8) Answers

Was Cassiopeia recently buffed?

Title.

View (1) Answers

cassiopeia at bot lane

has anyone tried to play cassiopeia at bot lane instead of an adc? as i don't main her nor am i at a high level of play i don't know how vibiable it can become. basicly here are some thoughts: 1. as an adc cass is a sustained damaged - low...

View (4) Answers

Timing of a DoTs first "tick"

So I wanted to ask this because I couldn't find it on LoLWiki. I've been under the impression that with DoTs the first tick of damage is done on application making it so that reapplying it in rapid succession will redo the first tick of damage....

View (0) Answers

Lich bane Cass

So I've noticed that every time you use [[twin fang]] on Cass, you get an auto attack in between the .5 sec cooldowns. So i was wondering how she would fair with a [[lich bane]] as compared to other build options

View (2) Answers

Next AP Mid to learn and why?

Hey, so I can't really decide which champion to learn next after I have finished with Evelynn. I play AP Mid in a fixed 5vs5 team so I need champions who are valuable in organised competitive play. Champions I currently am able to play on a decent...

View (4) Answers

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