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Recommended Items
Runes: ON-HIT STANDARD
+10% Attack Speed
+9 Adaptive (5.4 AD or 9 AP)
+10-180 Bonus Health
Spells:

Barrier
Flash
Items
Threats & Synergies
Threats
Synergies
Show All
Extreme Threats

Caitlyn
IF SHE KNOWS HOW TO PLAY THERE WILL BE A 100 MINION GAP BY THE END OF THE GAME TO HER ADVANTAGE, PLAY AROUND YOUR SUPPORT, FARM AND STAY EVEN IN CS AND RUSH VAMPIRIC SCEPTER ASAP

Lulu
MOST BROKEN SUPPORT WITH VAYNE, INCREDIBLE DUO. CAN NULLIFY EVERY MATCH-UP THERE IS IF PLAYED CORRECTLY.
Synergies

Lulu
MOST BROKEN SUPPORT WITH VAYNE, INCREDIBLE DUO. CAN NULLIFY EVERY MATCH-UP THERE IS IF PLAYED CORRECTLY.
Update log
26.3 - New description of use for Essence Reaver after experiencing different matchups
26.3 - Replaced Yun Tal with Storm Razor for Crit Vayne. Altered S16 Crit Vayne Build to suit META and matchups more. Added new feature S16 Crit Vayne Build with higher win % in-game
26.0 - Changed On-Hit-, Crit- and added custom S16 Vayne Build you can play around with and make your own. Added utility tree (CDR) as secondary when facing all-in Champions like Malphite to have Flash available earlier for his ultimate!
25.22 - Added Plated Steelcaps
25.11 - Switched Yun Tal to Kraken and added Bloodline runes for Crit Vayne
25.10 - Changed some of the matchups in hard difficulty after facing proper opponents
25.08 - Added Video Demonstrating Vayne Gameplay
25.08 - Added Jinx matchup.






































YouTube
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