First of all my english isn´t that well so don´t complain if there are some mistakes. Also this is my first guide so tell me your ideas and suggestions to make it better.
In this guide i want to show you my idea of an AP/AD Hybrid Warwick.

I take Marks of Insight for the magic penetration, because in my opinion o,95 macig pen. are better than 0.59 ability power.
I take Seals of Potency, becaus you need some AP too, but if you want to take Mana or Mana Regeneration Seals take them.
For Glyphes I really recommend Glyphes of Potency, because the 8,91 AP are really nice in the earyl Game.
And in combination with quintessences of potency you really have a pretty good damageoutput with your hungering strike.

My masteries explain them selves: Magicpenetration and ability power in the attack tree, Cooldown reduction in both trees and some other helpfull things in the utilities tree like mana or experience.

First you buy a Doran´s ring, because it is a nice item to stay on lane some longer. After this you get your boots. I recommend sorcerer´s boots, because of the so important magic pen. Following you buy Malady and Nashor´s Tooth for some AP and attack speed and a Morello´s Evil Tome for some AP, cooldown reduction and mana reg. Afterwards you should buy an Hextech-Gunblade, I really like this item an its active which you should use a lot. After this you sell your Doran´s ring and buy a Rabadon´s Deathcape for the AP and in addition you also sell your Malady and buy an Lich Bane for some AP and the great passive.

Your most important skill is your hungering strike, because it deals great damage. Your ultimate also is very important, due to its damage and stun. The next one is your blood scent since it gives you great speed to follow your enemies or get away from them. At Last your hunters call it gives you more attack speed but as you make more damage with your hungering strike it isn´t that important.

I like Flash and Ignite most since Flash gives you the ability to follow your enemie or to get away from them. I like Ignite becaus it prevents that there are luckers that get away with low amount of life.
But if you like some spells more you can also use them but I really wouldn´t take revieve or rally because I think these spells are really less usefull than others.

I hope this guide helps some of you and i hope you comment this gudie and tell me your opinion.