Twitch Build Guide by
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Twitch is champion which has the ablility to become invisible so al the main attack will be ganks, if you donot intend to use use twich as a gank player take my advise and choose another champion.
The runes I have chosen for twitch are based on armour penetration and attack speed as twitch is better played AD than AP so that is the reason then the pentakills you can choose the ones u prefere althoug I recomend you the penetration as the speed in high levels u have enough.
About the masteries these are really subjective as I preffere to increase damage rather than incre***ing my health or armour buta as I mentioned febore I think that masteries are so subjective that they are practically only used to guide but no to be foolowed step by step.
As for the items I filke this beeing the most important part if you want to kill and have a good team stat. the first thin you are gonna do is buy the dorans spade to increase your damage and health as twitch has very few health after buy health regeneration and speed after that buy some boots to be able to scape or follow finally spend all your money on dammage combined with health steal and attack speed