Build Guide by tajatysz
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Not Updated For Current Season
The masteries shown here are not yet updated for the current season, the guide author needs to set up the new masteries. As such, they will be different than the masteries you see in-game.
Cleanse- Cleanse is great to survive if you've got much DoT's on yourself, but i think it doesn't remove Ignite. It's good spell for Karthus, i use it often.
Ignite- Don't let your target escape, or make a perfect target for Requiem
Teleport- Good for defending towers, as well as to get back to your lane faster, or just get back to fight in enemy base after recalling, good spell for Karthus.
Clarity- Get it if you think you're low on Mana Regen, i usually dont use it, cuz Mana Regen from Archangel's Staff is enough for me.
Exhaust- Don't let your enemy escape or chase you, it's okay for Karthus but i dont use it, just spam Lay Waste under your feet if you're escapin, or a bit before enemy if you're chasing, i don't need exhaust, but it's okay spell.
Clairvoyance- It's a good spell but you need experience to use it well, im not usin it.
Flash- Good for escaping, it's great cause you can flash through walls.
Ghost- Also good for escaping and chasing, if you cant hit enemies with Lay Waste as they're chasin you.
Heal- It's good to stay at lane with low hp, but i dont use it, it's necessary in late game.
Revive-510 Sec Cooldown?Just NO!
Fortify- Save it for tanks and supports in your team.
Rally- Just no...
Smite- Useless, cause Karthus isn't good jungler.
As Karthus, i am usually going mid, but if enemy team has Yi on mid, change lanes with someone, Karthus on mid is a free kill for experienced Yi. I start up with Meki Pendant and HP Potion x2, to get some mana regen and let me stay on my lane longer, i usally recall at 1200 gold, when all enemies from my lane are dead, or if im seriously wounded. Grab Tear of the Goddes for better Mana Regen
Now you've got your ult, perfect to finish all those luckers! Grab Sorcerer's Shoes to be faster and get some Magic Pen. Dont be too aggresive, Karthus is squishy, you may die easily, but if you fight, just turn on Defile(get enemy into range if he's ranged fighter) and spam Lay Waste under Their feet, it makes really good damage, grab Archangel's Staff for AP, Mana Regen, and save your money for Needlessly Large Rod. Grab the rod, now you've got much AP and can start killing, but get Mejai's first to get those stacks.
Grab Zhonya's Ring, it gives you incredible ammmount of AP, and makes enemies easier targets, with just Zhonya and Archangel Staff im takin about 15% enemies HP with single Lay Waste. Get Lich Bane, now use Basic Attack after every Lay Waste, it'll deal nice damage thanks to Lich Bane.
I will update the description with more tips about skills, items etc. later, i shall also add pictures ;)