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A good mix of Ability Power, Attack Speed and Health with a small focus on Attack Damage.
For the item breakdown I go:
-Sapphire Crystal + HP Pots
Rod of Ages
Guinsoo's Rageblade or Aegis of Legion (eventually getting both)
As far the Quins go, you could take another magic pen or ability power @ 18 rune over the health one if you felt it would be better.
*Note - The order in which u get the Aegis of Legion vs the Guinsoo's Rageblade is up to you.