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LoL Best Middle Build Guides 2025

Build guides for Middle champions on MOBAFire. Find recommended items and runes by high ranked players to learn the best Middle builds. Create your own champion guide!



2025, Season 3 Guides // Patch 25.22
10
4137
Votes
126
LoL Champion Vel'Koz Build Guide
LoL Champion Vel'Koz Build Guide

[Patch 25.22] SEASON 15 Azzapp's Guide To Vel'Koz [MID/APC/SUP]

Guide by Azzapp updated November 11, 2025
  • In-depth
10
332
Votes
20
LoL Champion Qiyana Build Guide
LoL Champion Qiyana Build Guide

[S15] PATCH 25.22 QIYANA MID GUIDE - YT GUIDES AT END

Guide by Allyooops updated November 10, 2025
  • In-depth
10
2626
Votes
130
LoL Champion Yone Build Guide
LoL Champion Yone Build Guide

[15.22] Tempest's Challenger Yone Guide [In-Depth]

Guide by WayOfTheTempesst updated November 8, 2025
  • In-depth
  • Stream
10
252
Votes
16
LoL Champion Galio Build Guide
LoL Champion Galio Build Guide

[25.22] Hexeria's detailed Masters Guide to Galio

Guide by Hexeria updated November 7, 2025
  • In-depth
10
229
Votes
21
LoL Champion Katarina Build Guide
LoL Champion Katarina Build Guide

[25.22] PrestigeGalaxy's 6M+ Mastery Guide to Katarina! 🗡️

Guide by PrestigeGalaxy updated November 5, 2025
  • In-depth
  • Stream
9.8
593
Votes
36
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

💀[NEW SEASON 16] CASSIOPEIA - The POISON Queen of Midlane ☠ 💀

Guide by RezoneVerified updated November 12, 2025
  • In-depth
9.8
494
Votes
36
LoL Champion Lissandra Build Guide
LoL Champion Lissandra Build Guide

🍦 [ 25.22 - SEASON 16 - The MIDLANE ICE QUEEN OF DEATH! 🍦

Guide by RezoneVerified updated November 12, 2025
  • In-depth
9.8
61
Votes
2
LoL Champion Aurelion Sol Build Guide
LoL Champion Aurelion Sol Build Guide

[25.22] [Mid/Bot] Master OTP Season 15 Aurelion Sol Guide (+ Matchups Detail)

Guide by Event Horizon updated November 11, 2025
  • In-depth
9.8
587
Votes
87
LoL Champion Aatrox Build Guide
LoL Champion Aatrox Build Guide

[15.22] Aatrox Mega Guide 7m MP Master Top 15 worldwide

Guide by Veng Shotz updated November 11, 2025
  • In-depth
9.8
1320
Votes
53
LoL Champion Akali Build Guide
LoL Champion Akali Build Guide

[25.22] The Ultimate Guide to Akali the Rogue Assassin

Guide by iwontdominatelol updated November 10, 2025
  • In-depth
9.8
2333
Votes
163
LoL Champion Yasuo Build Guide
LoL Champion Yasuo Build Guide

[15.23] Tempest's Challenger Yasuo Guide [In-Depth]

Guide by WayOfTheTempesst updated November 8, 2025
  • In-depth
  • Stream
9.8
361
Votes
87
LoL Champion Caitlyn Build Guide
LoL Champion Caitlyn Build Guide

❄️🌙🧁Lethality / Burst Caitlyn Mid (+Crit)(+AD Stack)(All Champion Matchups)❄️🌙🧁

Guide by Zero macro updated November 7, 2025
  • In-depth
9.8
87
Votes
7
LoL Champion Aurora Build Guide
LoL Champion Aurora Build Guide

(25.22) (RANK 1 AURORA EUNE + ADVANCED COMBOS) THE ONLY MASTER AURORA GUIDE YOU'LL EVER NEED

Guide by AuroraAddict updated November 7, 2025
  • In-depth
9.8
52
Votes
4
LoL Champion Ahri Build Guide
LoL Champion Ahri Build Guide

[25.22] Peng's Ahri Guide 2.9mil+ points 10x Challenger

Guide by Peng04 updated November 7, 2025
  • In-depth
9.8
134
Votes
7
LoL Champion Viktor Build Guide
LoL Champion Viktor Build Guide

[25.22] - Viktor guide in depth - [ENG/ESP]

Guide by InTaggar updated November 6, 2025
  • In-depth
9.8
34
Votes
1
LoL Champion Twisted Fate Build Guide
LoL Champion Twisted Fate Build Guide

[25.22] Victorious Twisted Fate Guide for Season 15 | Jammed

Guide by Jammed updated November 6, 2025
  • In-depth
9.8
363
Votes
22
LoL Champion Rumble Build Guide
LoL Champion Rumble Build Guide

[Patch 25.19] Through the Fire & the Flames by Nahde (REBUILDING SLOWLY)

Guide by Xelikari updated November 6, 2025
  • In-depth
9.8
264
Votes
6
LoL Champion Hwei Build Guide
LoL Champion Hwei Build Guide

[25.22] Your True Colors - Complete Hwei Guide

Guide by Soft Headpats updated November 5, 2025
  • In-depth
9.7
181
Votes
15
LoL Champion Annie Build Guide
LoL Champion Annie Build Guide

[25.22] Rank 1 Annie Complete Guide | By Coach xblademojo

Guide by xblademojo updated November 11, 2025
  • In-depth
9.7
109
Votes
9
LoL Champion Veigar Build Guide
LoL Champion Veigar Build Guide

Guide of an Veigar OTP star zall I Challenger Veigar OTP 1353 LP Peak I

Guide by star zall updated November 8, 2025
  • In-depth
1 2 3 4 5 6 7 8 29 50
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League of Legends Champions:

AatroxAhriAkaliAkshanAlistarAmbessaAmumuAniviaAnnieApheliosAsheAurelion SolAuroraAzirBardBel'VethBlitzcrankBrandBraumBriarCaitlynCamilleCassiopeiaCho'GathCorkiDariusDianaDr. MundoDravenEkkoEliseEvelynnEzrealFiddlesticksFioraFizzGalioGangplankGarenGnarGragasGravesGwenHecarimHeimerdingerHweiIllaoiIreliaIvernJannaJarvan IVJaxJayceJhinJinxK'SanteKai'SaKalistaKarmaKarthusKassadinKatarinaKayleKaynKennenKha'ZixKindredKledKog'MawLeBlancLee SinLeonaLilliaLissandraLucianLuluLuxMalphiteMalzaharMaokaiMaster YiMelMilioMiss FortuneMordekaiserMorganaNaafiriNamiNasusNautilusNeekoNidaleeNilahNocturneNunu & WillumpOlafOriannaOrnnPantheonPoppyPykeQiyanaQuinnRakanRammusRek'SaiRellRenata GlascRenektonRengarRivenRumbleRyzeSamiraSejuaniSennaSeraphineSettShacoShenShyvanaSingedSionSivirSkarnerSmolderSonaSorakaSwainSylasSyndraTahm KenchTaliyahTalonTaricTeemoThreshTristanaTrundleTryndamereTwisted FateTwitchUdyrUrgotVarusVayneVeigarVel'KozVexViViegoViktorVladimirVolibearWarwickWukongXayahXerathXin ZhaoYasuoYoneYorickYunaraYuumiZacZedZeriZiggsZileanZoeZyra
Teamfight Tactics Guide