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Threats & Synergies
You almost always lose this match up as she can gap close so much. You want to go my "keep the carry alive build".
I'm not crazy high elo, but I did just hit Plat 1 playing with these exact runes builds and playstyle.
You will then max E first. It gives you health and a lot of AS which is great as you do build some AD and use your human form to poke them down with auto's.
You then max Q after that and R every time possible.
You will then finish with maxing W last.
You can take over the game if you get ahead. This will be even better once bot lane gets nerfed. You can face almost all other top lane champs, and a good amount you destroy.
She is kind of hard to play, I suggest looking at my vids for tips and tricks on how to play her effectively. If you get far behind you typically become useless. EXCEPT, now I have a new build. Check the next slide :)
You want to take the same first row runes, but you will instead take transcendence instead of celerity. Your build will also change.
IceBorn -> Shurelya -> Spirit if they have a bunch of AP otherwise, Athenes. You will then get randuins if you need the slow for your team, if not spirit into warmogs. You are no longer building to carry, you will play to your bot lane and keep your ADC full HP and a massive AS buff. All of the items you build help kite people trying to get to your back line and you can give massive heals to anybody who needs it. You are also tanky due to the items having armor and MR as well as your runes and items giving a lot of HP.