No, I haven't tried the build. But the reason I voted you down isn't because it doesn't work. It works, I know that. It's just that it doesn't really say anything I haven't heard before. Sorry man.

I'm sorry but I'm gonna have to agree with 19Appels on this. Nothing is special about this, yeah getting the boots first is a bit different, but it wont effect the game in a huge way. Guardians Angel is a pretty stupid item in most cases in my opinion, most of the time it just delays the fact your going to die.

As far as the Masteries go, going into Utility or Defense is fine either way, so nothing is special about that. Although, you are wasting a point in Mythical Vision and it should be in Good Hands.

It's a very small change to a build that has been on this site no less then 5 times I'm sure. The CD per level Glyphs are pretty garbage in my experience, and the description is very lackluster. This is a vote down.

its the order in which you buy the items thats important.... have you tried this build?

On your 'vastly different' runes, EVERYONE uses quints of fortitude, EVERYONE uses marks of insight, and half of all the people uses seals of vitality. The only thing different with the runes compared to other builds are the glyphs.
http://www.mobafire.com/league-of-legends/build/vladimir-maximum-hp-and-damage-ap-tank-nuke-build-13771
Thats a build with 3 out of four runes the same.
Then on the items, EVERYONE takes mejai's, EVERYONE takes rylai's, EVERYONE takes zhonya's, and almost everyone takes warmogs. The only thing you have different there is the angel.
So thats how vastly different you build is.
The desc. doesn't add anything either.

the item and rune builds are vastly different on other guides and contain + to mana? This is different. Try the build before you bag on it.

I don't see this build saying anything I haven't seen before. Nothing original, if you don't have anything new to say, why say it at all?