Vayne is one of my favorite new champions. She plays alot like Twitch because she's extremely fragile and very powerful. This guide is meant to get you started on playing her properly and is by no means a pro guide.

I'm also aware this guide lacks any survivability measures. She's quite the glass cannon and it's up to you if you want add any survivability.

Please give me feedback on my guide!

Pros
Melts faces if left alone
Strong Ganker
High dps
Great at pursuing fleeing enemies

Cons
Only does physical damage
FRAGILE
FRAGILE

Armor Pen runes since she's all AD and Health to combat her fragility. The glyphs aren't necessarily as important in my opinion.

This is the skill sequence for after you hit 6.

Final Hour
Readying herself for an epic confrontation, Vayne gains increased Attack Damage, stealth during Tumble, and quadruple the bonus Movement Speed from Night Hunter.

Tumble
Vayne tumbles, maneuvering to carefully place her next shot. She rolls toward the cursor and her next attack deals bonus damage.

Silver Bolts
Vayne tips her bolts with a rare metal, toxic to evil things. The third consecutive attack or ability against the same target deals a percentage of the target's maximum Health as bonus true damage. (Max damage vs. Monsters is capped)

Condemn
Vayne draws a heavy crossbow from her back, and fires a huge bolt at her target, dealing damage and knocking them back. If they collide with terrain, they are impaled, dealing bonus damage and stunning them.

Tumble gets maxed first because your attack speed at this point isn't fully developed, so the increased damage and lowered cooldown helps alot.

Now most builds have you start off with a Doran's Blade which is great health, damage, and 3% lifesteal. However, I prefer to start with a Vampiric Scepter. Sure, I lose out on some damage and health, but I personally think the lifesteal is worth it. This allows me far more flexibility as far as taking damage and pushing goes.

These are going to be your boots for obvious reasons. Attack speed scales very well with Vayne thanks to her W.

Stark's Fervor provides a great aura for teamfights and some good attackspeed as well as health regeneration which you'll need. Alternatively you can build a Bloodthirster instead.

Great attack speed, movement, as well as some critical strike. Great item, I personally love the movement boost which is great for catching runners. With this, no one can get away from your crossbow.

Great for softening up those more tanky champs and also gives attack damage and attack speed, a must have for Vayne.

This is where you make a judgment call as to what's needed at the time. Madred's is great if you're going against a team with low magic resist and high health. It also diversifies the type of damage you do. Infinity Edge puts your crit and damage up while The Bloodthirster provides extra damage and lifesteal if you think it's worth the farming.



Vayne invariably needs some sort of armor or health item or else you're just a walking loose, glass cannon ...whiich is how I love to play. However wiser players should definitely pick up something to protect in teamfights or ganks so that you don't die in about 3 seconds. Your call.

You may also be wondering why I don't have trinity force in my build like all the other Vaynes. Trinity Force, in my opinion, is a great item but is really expensive, so if you're racking up gold like no other, go for it.



Once it's late game and for some reason you've gotten everything you need, feel free to replace those old boots for a Phantom Dancer

Laning or Mid

Because Vayne is so fragile, mid can sometimes be a bad choice or it can pay off hugely. Vayne has wonderful harass, she can tumble very quickly at someone, let off a shot and then run out of range.
You can also harass pretty well even when the intended is in front of a tower. Quickly tumble close, condemn, and get out. If timed right, the tower will not have touched you and the target will have taken a good bit a damage being pinned into the tower.
If you're mid and up against a champion with a longer range harass, you may quickly end up feeding that person. Be careful when you're mid.
If you've just polished off your opposing mid-fielder use this chance to either ghost up to the top or bottom lane should a gank be opportune at that time.

Once again if you're laning you need to be careful as your health pool is tiny. Try your best to stay behind some creep or laning partner.

Vayne is a very powerful 1v1 champ provided you have the element of surprise and a nearby wall. Keep in mind towers and destroyed towers also count as terrain.
My favorite method of ganking is waiting in the fog and approaching from an angle perpendicular to the terrain and condemning the enemy into terrain.
1. Active Final Hour.2. Tumble into stealth so they don't see the imminent rape.3. Condemn their *** into a wall.
4. Proceed to rape.

Variations include pushing the champ towards or into a tower and letting it do some of the dirty work for you. It's not hard, use your imagination.

Running cause you're about to be raped?
If there aren't about four champions chasing you, but you still need to get away, decide when the best time to Condemn your pursuer. Then do it.
Guy still chasing you? Tumble early game is a little faster than walking, so try that.
STILL CHASING YOU? If all else fails, pop your Final Hour utilize that Tumble stealth so they can't see or slow you for a bit. Hopefully you've reached a tower or teammates at this point. If not, you overextended yourself and it's your fault.

Teamfights:
It's probably best to disable whomever's most likely to rape you in a teamfight. You are after all a/the carry and your mad damage output will likely make you the other team's focus. For this reason you should never be far from towers or teammates.

Tumble can aid in escapes and chases.
Condemn's stun can be pivotal in a fight.
Don't die alot. If you're not used to playing a fragile champion be careful.