LoL Best Vayne Build Guides 2025
Build guides for Vayne on MOBAFire. Find recommended items and runes by high ranked players to learn the best Vayne builds. Create your own champion guide!
2025, Season 3 Guides // Patch 25.22
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[25.22] VAYNE "ALL SHALL TREMBLE" SEASON 15 BUILD (2025)
[25.22] VAYNE "ALL SHALL TREMBLE" SEASON 15 BUILD (2025)
2025, Season 3 Guides // Other Patches
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[25.21] Challenger BR - Top 1 Vayne World S15 Guide !
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An Orbwalker's Guide to Vayne
2025, Season 3 Builds // Patch 25.22
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[25.22] Low Elo Vayne ADC anti tank pocket pick
2025, Season 3 Builds // Other Patches
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1 of 1 vayne build
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Burst vayne
Burst vayne
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Lethality Vayne
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Vayne))
2025, Season 2 Guides
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only vayne guide you will ever need
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[MASTER] [25.13] A guide to Vayne
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[15.13] Vayne guide by misterfirstblood v2
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<Master> S13 LostFish - Vayne: On Wings of Night (working on update)
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Vayne ADC Season 15 Cheat Sheet
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Here's a step-by-step guide for Vayne top lane in Patch 25.10, optimized for climbing ranked and destroying tanks.
2025, Season 2 Builds
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Jumpscare Vayne
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Vayne Lethality
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fiucina v3
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fiucina v2
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fiucina v1
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One tap vayne Crit/Letha
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