It's time for the 2025 Season 1 Guide Contest! Create or update guides during the following 6 weeks to compete for the $3,750 prize pool. 🏆
LoL Best Vayne Build Guides 2025
Build guides for Vayne on MOBAFire. Find recommended items and runes by high ranked players to learn the best Vayne builds. Create your own champion guide!
2025, Season 1 Guides // Patch 25.S1.1
![]()
An Orbwalker's Guide to Vayne
An Orbwalker's Guide to Vayne
Season 14 Builds // Patch 14.24
![]()
Ultimate Patch 14.24 Vayne Builds
![]()
Vayne Guide Basic
Season 14 Guides
![]()
[14.23] Vayne guide by misterfirstblood
![]()
<Master> S13 LostFish - Vayne: On Wings of Night (working on update)
![]()
[14.16] The Ultimate Vayne ADC Guide *updated*
![]()
SOLO CARRY Vayne top lane
SOLO CARRY Vayne top lane
![]()
Vayne complete guide
![]()
[ 14.12 ] Lethality / AD vayne
![]()
High Octane Vayne
![]()
Vayne, the On-Hit Menace (Patch 14.10)
![]()
14.10 BROKEN FREE ELO CRITICS VAYNE
![]()
Vayne - for every occasion - by s2 expert
![]()
[14.1] [Master] Leaf Vayne Guide - Season 14
![]()
[14.1b] Mastering Vayne's On-Hit Build for Maximum Impact [READ NOTES]
![]()
Vayne
Season 14 Builds
![]()
VAYNE -> Diamond guide 14.23
![]()
Guide For Daniel to melt tank
![]()
Vaybe tank
Vaybe tank
![]()
>=====> [14.23] Hentrion's Vayne: Free PDL <=====<
Create Your Champion Build Guide
Share your strategy for your favorite champion with the largest League of Legends community!
CreateYour Guide!
