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LoL Champion Build Guides: Karthus

Karthus RP Cost 790 Karthus BE Cost3150
Pick 78%
Win 51%
Pick 12%
Win 55%
Pick 8%
Win 52%
+ Wishlist

Karthus The Deathsinger

Find the best Karthus build guides for League of Legends Patch 10.21. The MOBAFire community works hard to keep their LoL builds and guides updated, and will help you craft the best Karthus build for the S10 meta. Learn more about Karthus' abilities, skins, or even ask your own questions to the community!


Karthus Build Stats

Patch 10.21: 401596 matches scanned * Each section of the build is rated independently of the others

Karthus's Runes

Karthus's Best Runes 51%

Win Rate 8421 Games

  • 1
  • 2
  • 3
Domination
LoL Path: Domination
LoL Rune: Dark Harvest
Dark Harvest
LoL Rune: Cheap Shot
Cheap Shot
LoL Rune: Eyeball Collection
Eyeball Collection
LoL Rune: Ravenous Hunter
Ravenous Hunter

Precision
LoL Path: Precision
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Coup de Grace
Coup de Grace

Second Best

Karthus's 2nd Best Runes 55%

Win Rate 1716 Games

Domination
LoL Path: Domination
LoL Rune: Dark Harvest
Dark Harvest
LoL Rune: Cheap Shot
Cheap Shot
LoL Rune: Eyeball Collection
Eyeball Collection
LoL Rune: Ravenous Hunter
Ravenous Hunter

Precision
LoL Path: Precision
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Last Stand
Last Stand

Third Best

Karthus's 3rd Best Runes 68%

Win Rate 62 Games

Domination
LoL Path: Domination
LoL Rune: Dark Harvest
Dark Harvest
LoL Rune: Cheap Shot
Cheap Shot
LoL Rune: Eyeball Collection
Eyeball Collection
LoL Rune: Ravenous Hunter
Ravenous Hunter

Precision
LoL Path: Precision
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Last Stand
Last Stand

Karthus's Summoner Spells

Karthus's Best Summoner Spells 50%

Win Rate 20074 Games

  • 1
  • 2
  • 3

Second Best

Karthus's 2nd Best Summoner Spells 55%

Win Rate 472 Games

Exhaust Smite

Third Best

Karthus's 3rd Best Summoner Spells 52%

Win Rate 63 Games

Smite Ignite

Karthus's Starters

Karthus's Best Starter Items 50%

Win Rate 20320 Games

  • 1
  • 2

Trinket

Karthus's Best Trinket 51%

Win Rate 13700 Games

  • 1
  • 2
  • 3

Second Best

Karthus's 2nd Best Trinket 47%

Win Rate 5725 Games

Warding Totem

Third Best

Karthus's 3rd Best Trinket 48%

Win Rate 1227 Games

Farsight Alteration
Don’t forget
to Buy Wards

Karthus's Ability Order

Karthus's Best Ability Order 68%

Win Rate 3176 Games

  • 1
  • 2
  • 3

Second Best

Karthus's 2nd Best Ability Order 66%

Win Rate 1082 Games

Third Best

Karthus's 3rd Best Ability Order 60%

Win Rate 84 Games

Patch 10.21: 401598 matches scanned * Each section of the build is rated independently of the others

Karthus's Runes

Karthus's Best Runes 71%

Win Rate 58 Games

  • 1
  • 2
  • 3
Domination
LoL Path: Domination
LoL Rune: Dark Harvest
Dark Harvest
LoL Rune: Cheap Shot
Cheap Shot
LoL Rune: Eyeball Collection
Eyeball Collection
LoL Rune: Ravenous Hunter
Ravenous Hunter

Precision
LoL Path: Precision
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Last Stand
Last Stand

Second Best

Karthus's 2nd Best Runes 56%

Win Rate 1190 Games

Domination
LoL Path: Domination
LoL Rune: Dark Harvest
Dark Harvest
LoL Rune: Taste of Blood
Taste of Blood
LoL Rune: Eyeball Collection
Eyeball Collection
LoL Rune: Ravenous Hunter
Ravenous Hunter

Precision
LoL Path: Precision
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Coup de Grace
Coup de Grace

Third Best

Karthus's 3rd Best Runes 55%

Win Rate 431 Games

Domination
LoL Path: Domination
LoL Rune: Dark Harvest
Dark Harvest
LoL Rune: Cheap Shot
Cheap Shot
LoL Rune: Eyeball Collection
Eyeball Collection
LoL Rune: Ravenous Hunter
Ravenous Hunter

Precision
LoL Path: Precision
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Coup de Grace
Coup de Grace

Karthus's Summoner Spells

Karthus's Best Summoner Spells 57%

Win Rate 1931 Games

  • 1
  • 2
  • 3

Second Best

Karthus's 2nd Best Summoner Spells 53%

Win Rate 428 Games

Flash Teleport

Third Best

Karthus's 3rd Best Summoner Spells 49%

Win Rate 259 Games

Flash Heal

Karthus's Starters

Karthus's Best Starter Items 55%

Win Rate 2844 Games

  • 1

Trinket

Karthus's Best Trinket 57%

Win Rate 1356 Games

  • 1
  • 2
  • 3

Second Best

Karthus's 2nd Best Trinket 52%

Win Rate 1255 Games

Warding Totem

Third Best

Karthus's 3rd Best Trinket 57%

Win Rate 127 Games

Oracle Lens
Don’t forget
to Buy Wards

Karthus's Ability Order

Karthus's Best Ability Order 69%

Win Rate 115 Games

  • 1
  • 2
Patch 10.21: 401602 matches scanned * Each section of the build is rated independently of the others

Karthus's Runes

Karthus's Best Runes 67%

Win Rate 123 Games

  • 1
  • 2
  • 3
Domination
LoL Path: Domination
LoL Rune: Dark Harvest
Dark Harvest
LoL Rune: Cheap Shot
Cheap Shot
LoL Rune: Eyeball Collection
Eyeball Collection
LoL Rune: Ravenous Hunter
Ravenous Hunter

Precision
LoL Path: Precision
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Coup de Grace
Coup de Grace

Second Best

Karthus's 2nd Best Runes 59%

Win Rate 116 Games

Domination
LoL Path: Domination
LoL Rune: Dark Harvest
Dark Harvest
LoL Rune: Taste of Blood
Taste of Blood
LoL Rune: Eyeball Collection
Eyeball Collection
LoL Rune: Ravenous Hunter
Ravenous Hunter

Precision
LoL Path: Precision
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Last Stand
Last Stand

Third Best

Karthus's 3rd Best Runes 58%

Win Rate 195 Games

Domination
LoL Path: Domination
LoL Rune: Dark Harvest
Dark Harvest
LoL Rune: Taste of Blood
Taste of Blood
LoL Rune: Eyeball Collection
Eyeball Collection
LoL Rune: Ravenous Hunter
Ravenous Hunter

Precision
LoL Path: Precision
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Coup de Grace
Coup de Grace

Karthus's Summoner Spells

Karthus's Best Summoner Spells 53%

Win Rate 1195 Games

  • 1
  • 2
  • 3

Second Best

Karthus's 2nd Best Summoner Spells 57%

Win Rate 304 Games

Flash Ignite

Third Best

Karthus's 3rd Best Summoner Spells 50%

Win Rate 947 Games

Flash Teleport

Karthus's Starters

Karthus's Best Starter Items 52%

Win Rate 3303 Games

  • 1

Trinket

Karthus's Best Trinket 50%

Win Rate 1746 Games

  • 1
  • 2
  • 3

Second Best

Karthus's 2nd Best Trinket 57%

Win Rate 816 Games

Farsight Alteration

Third Best

Karthus's 3rd Best Trinket 55%

Win Rate 166 Games

Oracle Lens
Don’t forget
to Buy Wards

Karthus's Ability Order

Karthus's Best Ability Order 70%

Win Rate 252 Games

  • 1
  • 2

Karthus Skins

Karthus' Abilities

Ability Range Cost Cooldown
Karthus's Death Defied
Death Defied Karthus's Passive Karthus's Passive
Self
Karthus's Passive
Karthus's Passive
Upon dying, Karthus enters a spirit form allowing him to continue casting spells for 7 seconds. During this time his abilities cost no mana.
Q
Karthus's Lay Waste
Lay Waste Karthus's Q Ability
875
20 / 26 / 32 / 38 / 44
1
Karthus briefly reveals the target area which he detonates after a 0.5-second delay, dealing 50 / 70 / 90 / 110 / 130 (+30% of ability power) magic damage to all enemies within, doubled when hitting only one target.

Lay Waste's damage is reduced by 15% against monsters.

During Death Defied, Lay Waste will cast at maximum range if cast beyond that.
W
Karthus's Wall of Pain
Wall of Pain Karthus's W Ability
1000
70
15
Karthus creates a 800 / 900 / 1000 / 1100 / 1200 distance wide wall at the target location for 5 seconds. The wall reduces the magic resistance of enemies who pass through it by 15% for 5 seconds and applies a 40 / 50 / 60 / 70 / 80% slow which drops to half effectiveness after 1 second and then decays over the remaining debuff duration.
E
Karthus's Defile
Defile Karthus's E Ability
425
30 / 42 / 54 / 66 / 78
0.5
Passive: Karthus restores 20 / 27 / 34 / 41 / 48 mana whenever he kills an enemy.

Toggle: Drains 30 / 42 / 54 / 66 / 78 Mana every second. Deals 7.5 / 12.5 / 17.5 / 22.5 / 27.5 (+5% of ability power) magic damage every 0.25 seconds to all nearby enemies. Deactivating Defile deals 1 tick's worth of damage.

Defile cannot be toggled off during Death Defied, but it can be while channeling Requiem.
R
Karthus's Requiem
Requiem Karthus's Ultimate (R) Ability
Self
100
200 / 180 / 160 / 160 / 160
After channeling for 3 seconds, Karthus deals 200 / 350 / 500 (+75% of ability power) magic damage to all enemy champions (regardless of distance).

Questions About Karthus

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