SPELLS

Flash - For obvious reasons
Heal - For safety and TFs
TP - If the enemy team isn't dangerous for you or you want to get ahead in the lane.

RUNES

I like comet because it gives you consisten damage and you are able to poke the enemy team on the lane, in chokepoints or when you aram.
Manaflowband is for Mana bacause Ziggs can get OOM in long fights pretty quick. Also
you want Transcendence for the Damge and CDR. Gathering Storm is for Damage aswell.

As second runepage I go with the Stopwatch and Cookies for the lane and to be more safe or with Domination when the matchup is easy.

If you want to snowball or be stronger in the lategame you can go with DH.

THE CORE

My fav Corebuild is the "Unkillable king of the botlane" bacause it gives you Mana, Damge and a good healthpool.
The damagebuild is the normal Ziggs build. You have more damage early but are weaker in the midgame and lategame.
The "Spam the bombs" build is really just for lategame and spamming your abilitys in TFs but I dont recommend it.

THE ITEMS

First you want to rush the Rod of Ages to get the 10 stack as fast as possible.
After that you go for your boots.
Then the Ludens Echo which gives you a lot of damage and Mana.
As your last coreitem go for the Oblivion Orb and build the Morellonomicon later in the game. If they have a lot of healing you can build it into Morellonomicon earlier. (If they have much MR you should build a voidstaff instead.)

Lich Bane - Build it for Damage (it has a good synergy with your passive)
Liandrys - Its good for DPS and a even bigger healt pool. It helps against tanks too
Rabadons - If you are ahead or want to finish the perfect build take the hat. It
gives you a huge amout of AP.
Rylais - I dont really recommend it but the slow it good for kiting and TFs
Voidstaff - Build it when the enemy team has a lot MR.
Protobelt - I dont recommend this either but the dash can be used for safety and HP
combined with AP works out pretty well.
Twinshadows - Its cheap, it slows, it gives Ap. The item is not bad but there are
better options.
Zhonyas - The stopwatch makes you even more unkillable and te armor is good against
high AD teams.
Banshees - Its good against high AP teams and longrange enage.

Never forget: Always adapt your itembuild to the game.

EARLY GAME

In easier matchups you can trade a lot and go for kills. In harder matchups you can farm savely und tower and poke the enemy botlane to set up a gank. Ziggs W is good for destroying towers so make sure to abuse it when you can. Most of the times you have to adapt your lane to what your sup is doing.

MID GAME

Try to take the bot tower as fast as possible. After that you can group mid with your team or swap lanes with your toplaner to push the other towers aswell. Ziggs is good in a group or siege situation so focus on that.

LATE GAME

In the lategame you want to TF. If you can try to fight around objectives or in chokepoints because Ziggs shines there even more. If you win the fights, get baron or can siege safely you should push towers and win the game. With this Ziggs build you can be a little bit riskier in TFs because of your huge healthpool but you need to figure out your playstyle in a few games. So stop reading and start playing! Explosion first, questions later!