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Your build is pretty good except for one little point...: 2X Rabadon's cap is impossible to get... I've been playing with Karthus for six months now and I was only able to get 2 of these in one or two games... Maybe consider getting Rylai's Crystal Sccepter earlier than a second cap.
I wanted to agree with you on the point that KARTHUS IS AND WILL REMAIN OP !!! Is passive is one of the funniest i've seen in video games in general !!! So many players rage quit right after they thought they killed you and that you can blast them from afar after death with requiem !!!