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It's not much, but you can't forget that besides the runes as you mentioned. Malady will provide you with flat magic penetration, in almost the exact amount as the Sorcerer's Shoes. And then you have the 15% magic penetration (which is not too much unless they stack resist) from masteries, but gives you more or less a head start.
I would obviously go for Void Staff (since it gives you percent based magic penetration)if I noticed alot of people going for resist, but it rarely feels necessary. I will however include the Sorcerer's Shoes because of it's flat magic penetration will help you early on, but in my eyes Malady will take care of the early "magic penetration problem".
Thanks for your thoughts though, and good luck with your own guide <:
Those free early kills will still be avaiable, just leave the mass harrassing to your partner if possible. :>