Well I played with this one + one small mod. Instead of two blodrazers I finished with a Frozen Mallet. With all our inhibitors destroyed I felt I had to do something. Quadra -> GG.

End game stats:
29-9-15... 215 minons... 22.1 K G

Late game dmg is not good enough with this build :/
The second build doesn't build defences early enough to counter a AP carry, or LW to counter a strong tank.

True. It's a lot easier to last hit when you have one or more Doran's Blades. The Madred's Razor helps a bit as it does give you the attack damage of 1.5 doran's blade. It also gives you a chance of doing additional damage. I feel that it's not as hard to last hit as Vayne by, if you really needed to, tumbling for the attack reset and more damage. Thanks for your perspective! =]

i pretty always use this guide and it has served me well! great job!

Even if vayne is one of the few ad carries that can be built unconvetional Ionic Spark makes it HARD to farm and easy to miss last hits. Nothing else to say, pretty accurate guide.

Attack speed on vayne = down any opponent in seconds

Great

Oh wow! I didn't even think about Dominion ahaha. I'm glad you tried it out! =]

good

great build, especially for dominion!

Hey man, never seen such an unique build on Vayne :D Ima try it out one day XD
but i would get 1 tiamat atleast

Check out my guide :p its also vayne guide

Thanks for trying it out! =]