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mark of the ***iasin gives 25x2 flat damage while crescent blow only gives another 25-30
so imo mark of the assassin should be used at level 1-3-5-7-9 instead of 1-4-7-8-9
Mark ok the Assasin give 50x2 flat at level 1 and it's better to actualy get all 3 spells and be able to start performing a rotation at lvl 3. I'm only giving recommendation if you want to do 1-3-5-7-9 it's up to you. :)
so imo mark of the assassin should be used at level 1-3-5-7-9 instead of 1-4-7-8-9
btw check out my Gragas-build ^^