Hey There!
Thanks for stumbling upon this poorly written guide about Twisted Fate.
I would just like to say,
If your going to downvote, let me know why!
Enjoy :)

These runes are NOT permanent.
These simply my generic bursty AP runes.
Tell me in the comments what you think would go better here. Thanks :D

I have chosen these masteries because to me, They simply leak of Twisted Fate.
22/0/8 or 23/0/7 if you want to max out the Attack speed instead of leaving it at 3.
This is all your decision. I cannot and will not control how you play TF.
Once again. Let me know in the comment section what I should change and your thoughts.

Now Most of you may have just skipped right on down here. So since your probably loading a match right now I'll give you guys the speedy version:
Boots of Speed and Health Pots x3
First B: If good farm Needlessly Large Rod if not so much Boots of Swiftness/Sorc Shoes
Guisinoos Rageblade Your first major item. Get this ASAP
Hextech Gunblade Second major item. Can be switched with Rageblade for more early survivability.
Rabadons Deathcap If you get this far its time to deviate.
If the game is practicly over and your stomping face, Deathcap is your item.
If your not doing so good and the game is hurting Rylais Crystal Scepter is your way to go. Health and a slow is better then burst at this point. This doesnt have to be an Oh **** item. You can add this into your reg. build.
Remember I cannot and will not make you play a certain way.
This just my way of playing TF.

For your first skill you want.
You get this because Level 1 damage simply isnt enough.
Pick a Card's utility is so much better.
Maxing out Wild Cards first give you your Bursty aspect. Run in Gold card Wild Cards runs behind em rinse and repeat!
It works really well w/ Rylais as well.
Maxing out Pick a Card 2nd will help you with your Gold card Timer or if your OOM Blue Card that mana right on back. So on and so forth.
Stacked deck is maxed out last simply because its level 1 ability is just fine w/ how i play.
But do remember! By watching your stacked deck stacks you can get yourself out of the good TF category and put yourself in the GODLIKE! "Pentakill!" Status.
Now TF's infamous ult Destiny.
Hit it once you can see EVERYONE!! Even invisible champions. So for those sneaky Shaco's and Twitches that get away you get a free clean up.
A trick I was taught once for ganking was:
Load of Stacked Deck to your 4th card. Load up gold card. Tele in. Gold card+Stacked deck damage. Wild cards ??? PROFIT!
Easy Right? WRONG! So very wrong, Getting that 4th card loaded and remembering to Gold card first is actually quite difficult considering you'll end up getting screamed at by your team if you fail your gank.
God Dam the LoL non-ranked community.

Teleport is a given on TF. If you don't use teleport on TF please let me know why.
Not once have I been supplied with a good enough reason.
Now Exhaust or Ignite or Flash or whatever.
The 2nd one is purely preference. I use exhaust because of 1v1 situations are not to healthy for TF unless the Enemy is running from him or missing 75% of his health :P
TF is and Assassin pusher. So he needs to be doing that. Teleport in on a minion wave take down the tower. If everyone is mia check your ult the CD is short.
If they are coming you have GATE now. GTFO survive go spend your 150 gold :D

So far this is all I have.
Please let me know what i need to change and Add or Remove!
Thanks for reading
GLHF!