I have highly revised this build since I started making it. Now, a new masteries tree is out and I'm playing around with it a bit. I believe I have found a good set for our lovely rat.

Twitch has been nerfed to hell and back. I've stuck with him through many of these changes. Luckily, with the Dominion update, there's a new map to prowl, open ganking areas, and a few new items to help shred your foes to pieces. This is played very differently than a standard Classic game.

Consecutive wins:

Games over 2000 points, consistently:

This game was won at a 4/5 disadvantage. This may be the best game I've ever played. Clutch win with 8 pips left on our side.

Another game over 2000 points:

Another game over 2000 points:

Please send me links to your games, and I might post them.

Pros:
* Easily one of the most effective assassins in the game.
* Free movement around map.
* Backcap's effectively
* Can level a whole team in a teamfight when someone else initiates.
* Ganking master of LoL.
* Can escape and chase effectively.

Cons:
* Easily countered with oracle and ignite.
* Glass cannon (though with lifesteal you can take a bit more damage).
* Cannot initiate team fights.

***Will update this list as I have time***

Completely Updated.

I have updated yet again. I find that starting with a Prospector's Blade and boots are the best way to go. the 200 HP and 20 damage make a huge difference early game. Not to mention the 5 lifesteal is the icing on the cake. Build into Bezerker's Grieves as soon as possible. From that point on, it's about maximizing damage, and that's it. I tend to go for BF sword items. It's flexible, but total damage output is the way to go. I change and update the items all the time, so don't think it's in stone. But definitely go damage.

Deadly Venom
Poison that stacks up to 6 times, and deals true damage. keep stealthy enemies from going invisible with this. As well, Watch as many enemies run away with little health and trololol when they die off your screen. Did an enemy jump you? They'll regret it when they die shortly after you do.

Ambush

This skill is what makes Twitch... well, Twitch. Your Q will make you go invisible. The longer you stay stealthed, the longer you get an attack speed buff when you pop out. Attacking anything or using any skill will cause you to leave stealth, as well as taking damage.

Venom Cask
Twitch's version of how a slow should work. More stacks of venom = slower and slower for your enemies. This is another great skill to help you run down fleeing enemies, or slow charging enemies while you escape.

Expunge
Twitch's bread and butter. After hitting enemies (6 times if you're efficient) you can pop expunge and watch what little health they have *poof* dead. This works in team fights very well with your ulti. Quadra's aren't too rare with this ability, considering the range is almost your whole screen.

Spray and Pray
Your beloved "R" key. You can now fire big f'ing shots through multiple enemies in a straight line. And poison all of them. Expunge. Rinse and repeat as necessary. Perfect for teamfights.




Gameplay General:
So, you know the skills. Using them smartly is another thing. First, you have to know Twitch's place in Dominion. He's the perfect assassin, having an open map and many getaway directions. I mainly lurk mid invisible, wait for an enemy to attempt to take our seemingly undefended tower. As soon as they get there and initiate the cap, I pop out, hit them a few times, debilitate them, and hit them a few more, then expunge. This is usually enough to take down even a beefy champ. As well, if you have your ulti up, You could even take out 2 champs.

You should be able to easily average 15 kills a round. Enemies are too busy with defending and attacking to remember "Oh ****... where's that rat?". Use towers to your advantage. Defending gives you a much better survival rate than attacking.

Gameplay- Early Game:
Firstly, always ask in pregame if you can cap mid. If they give you trouble, just mention that you're one of the squishiest champs. Be ready to cap it ASAP when the game starts. All other 3 should go straight for windmill, don't let anyone help you. After capping, ghost to the speed shrine on the way to windmill, and go invis as you leave the shrine. Take a look at the battle that should be going on, and choose your placement wisely. Pick a poor spot and you just wasted a death, and probably lost top for the team. Target weak champs, and exhaust strong ones. Save teammates if possible. If the other team is attempting to cap windmill, just engage it and counter-cap to cancel theirs if you can't get close enough to damage the enemy without dying.

Defending a Point:
Believe it or not, Twitch is a great defender. In fact, you'll see your k/d/r and points skyrocket if you can defend well. What I like to do is sit in stealth either on point or behind it in the bushes. Unknowing backcappers get exhausted, ulti'd, then debilitated to death. Even if 2 are trying to cap, you can ulti through both forcing them to jump you or run. Either way, help should arrive shortly if you ping it and teammates listen. A death is well worth keeping a point for your team.

BACKCAPPING:
This is a great tactic for Twitch. Just like backdooring in Classic Mode, Twitch can move unseen through the enemy ranks. Just mosey on over to the enemy team's upper tower and wait for them to all be busy attacking other towers. Then just take it from them. Laugh in all chat, then disappear. If they are at the towers nearest you, you'll probably only have time to neutralize the tower. When they get within range Debilitate them and run away in stealth. Even if you don't take the tower for your team, they don't have it. And they had to waste manpower that could be defending other towers to deal with you. Consider this more of a "disruption" tactic.

Communication:
If you don't communicate with your team (ping ganks, and warn teammates to lure their chaser your way), then you will fail. But, if you do communicate and set up the situation in your favor, then you'll have a good chance at winning. When ganking with a "lure" (a teammate that would surely die if they were to fight themselves), you can turn the tide of the battle instantly. Stay in stealth, and get behind the enemy closes to your teammate. If there are 2, then get behind both to use your ulti. Teammate should help draw them past you. Now you have 2 enemies sandwiched with your ulti tearing them limb from limb.

Fashionably Late:
As the section title indicates, Twitch should be fashionable late. Firstly, always ask in pregame if you can cap mid. If they give you trouble, just mention that you're one of the squishiest champs. Be ready to cap it ASAP when the game starts. All other 3 should go straight for windmill, don't let anyone help you. After capping, ghost to the speed shrine on the way to windmill, and go invis as you leave the shrine. Take a look at the battle that should be going on, and choose your placement wisely. Pick a poor spot and you just wasted a death, and probably lost top for the team. Target weak champs, and exhaust strong ones. Save teammates if possible. If the other team is attempting to cap windmill, just engage it and counter-cap to cancel theirs if you can't get close enough to damage the enemy without dying.

Wait in team battles for initiation and the first couple skills to be used up by the enemies. Once they have ulti'd or exhausted a decent amount of mana, pop out with your ulti. Be careful to target someone that puts the most number of enemies between you and him. The whole enemy team's health will drop very quickly. Next, expunge as the begin to scatter, followed quickly by Debilitate. They should all be dead (or close to it) and now slowed if they managed to survive. Pick 'em off.

Knowing when to die:
I would say that at least half my deaths are planned. I know it sounds weird, but here's the method to this madness... With respawn times so quick, I often will kamikaze if defending a point Outnumbered. I know I can at least kill one, and quite possibly both if ult is up. I also know, if it is more than 2v1 I will 90% die, unless my ult it up and can tare them a new one. So, take out as many as possible and make sure the remaining enemies are hurt very badly. This way, I can respawn, head back out there, and hopefully my teammates can swing and clean them up. I tend to rarely ever B. I buy when dead.

I will be updating this guide in the next few days. Please don't troll it, as it's still WIP. Any suggestions would be nice.

To Do List:
* Get feedback on guide
* Waffles for dinner
* Try out same items, different order and see if there's a big difference
* Perhaps Mobility Boots instead of Bezerkers Grieves?

10/14/11:
Created barebones for the guide.

10/15/11:
Tweaked the build

10/18/11:
Added Epilogue

10/21/11:
Added survivability to the gameplay section.
Added Changelog.
Added Alternative Builds section.

10/23/11:
Overhauled the item sequence, and changed out Heal for Ignite

11/11/11:
Switched out Ignite for Exhaust.

11/16/2011:
Updated masteries to reflect the season 2 update.
Updated screenshots to include matches with more than 2000 points.
Changed name from F'ing invisable rat.
Updated build to reflect the games played at over 2k pts.


11/17/2011:
Updated screenshots.
Added "Defending a Point" to gameplay guide.
Fixed some formatting issues.

11/29/2011
Added "Knowing when to die" to gameplay section.
Reported troll downvote.

12/9/2011
Added Prospector's Blade to the starting build.

12/27/2011
Changed out Seals of Might for Dodge runes.