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Abilities (Human form):
Spider Swarm (Passive): Elise’s Human Form spells will ready a spiderling when cast on an enemy.

Neurotoxin: Elise damages a target based on its current Health.

Volatile Spiderling: Elise releases a venom-gorged spiderling that explodes when it nears a target.

Cocoon: Elise fires a skillshot that stuns the first enemy struck.

Spider Form: Elise transforms into a menacing spider with new abilities. While in Spider Form, Elise deals magic bonus damage on attack and has increased Movement Speed, Armor, and Magic Resistance. Each level of her ultimate allows Elise to summon an additional spiderling.

Abilities (Spider Form):
Spider Swarm (Passive): Elise summons her spiderlings to fight by her side. Spiderlings deal physical damage and take reduced damage from multi-target abilities.

Venomous Bite: Elise lunges forward and bites her target, slowing them and dealing bonus damage based on how low its Health is.
Skittering Frenzy: Elise and her spiderlings gain Attack Speed and heal her on each attack.

Rappel:
On enemy cast: Elise and her spiderlings ascend high into the air and descend upon an enemy target.

On ground cast: Elise and her spiderlings ascend high into the air, becoming untargetable for two seconds. Casting Rappel on a nearby enemy during this time will descend upon your target.

Human Form: Elise transforms into a human form with new abilities. Each level of her ultimate allows Elise to summon an additional spiderling.

Vicious and elegant, Elise's charismatic grace lures the innocent and greedy alike into her web of deceit. While her victims may discover her true intentions, no one has ever lived to reveal what dark secrets lie behind her enigmatic guise.
In dark halls, hidden from society, Elise preached the word of a mythical spider god. Her desperate followers hungered for the god's favor, believing its blessings to be the source of Elise's vibrance and power. When Elise proclaimed that she would lead a pilgrimage to the spider god's shrine, she selected only her most devout disciples to join her. Ecstatic, the chosen few followed her blindly as she led them on a perilous journey across the sea. When they came ashore at their final destination, the mysterious Shadow Isles, Elise led them to a cavern shrouded in webs. Expecting a shrine, the group looked to their priestess in confusion. She turned to the crowd and raised her arms in triumph, revealing strange, spider-like legs that grew out of her back. Seeing her terrifying true form for the first time, Elise's followers turned to flee, but she conjured magical webs to trap them. With her victims ensnared, she turned to face the cave and uttered a screeching cry. An enormous undead spider-beast emerged from the darkness, dragging its hideous bulk on thick, pointed legs. Elise's followers could only scream as the monstrous spider ate them alive. She approached the sated creature, extracted its venom, and drank the strange substance. An immediate sense of rejuvenation flowed through her veins. With mortality delayed once again, Elise left to rejoin her congregation. They were overjoyed to hear that their fellows had chosen to remain at the spider god's sacred home. Elise reassured her disciples that she would lead another pilgrimage in due time. The spider god would be waiting.
"The truly faithful need not fear the spider's embrace."
―Elise
"Elise's regal demeanor and captivating charms belied the feeling of dread she conjured in the pit of my stomach. Something in the deceptively musical timbre of her voice gave the impression there was a monstrous beast locked away beneath that unearthly smile. I looked around at her spellbound followers, and could not shake the feeling that they were ensnared like insects in a web, awaiting some horrible fate."
― Riven
"As the fog parted and I first beheld the Shadow Isles, I sensed immediately that something was amiss. From the mysteriously placid waters of the bay to the dead calm of the night air, an eerie stillness gripped the place – even the sea and sky. Even as I made ready to go ashore, the crew begged me to return at once to the mainland."
―Elise
"Despite its size, the immense forest loomed like a sepulcher around us, and the dank air and unnatural stillness bred increasing feelings of paranoia and dread. My companion begged me to turn back, but some primal yearning spurred me onward, deeper into the gloom."
―Elise

Upon Selection
"Only the spider is safe in her web."

Movement
"We must all make sacrifices."
"Every web, a masterpiece."
"I can show them the way to divinity."
"I know the true path."
"I know what lurks in the shadows."
"My true beauty is beneath the skin."
"There's nothing to fear."
"Pull the strings. Watch them dance."
"They need... guidance."

Attacking
"Dangling by a thread."
"Ah, the tangled webs we weave."
"Weak willed fools!"
"I have... refined tastes."
"The spider demands sacrifice."
"It will all be over soon."

Joke
"I hear a man likes a lady with legs."
"Hmm, why so tense? Relax."

Taunt
"Come closer, I don't BITE!"
"The spider, I. And you, the fly."

Spider Form is most effective at finishing off enemies with low health; Human Form's Neurotoxin does more damage to healthy foes.
Spider Form and Spider Form abilities do not cost mana and can be prioritized when you are trying to conserve mana.
Use Spider Form when escaping , as the bonus armor and magic resist will make you tankier and you can use Venomous Bite as a last resort on minions or monsters and Rappel will make you untargetable. Being in this form also grants you 10 bonus unlisted movement speed.
Use Spider Form to get back to lane faster, is it gives bonus movement speed.
Rappel can not see stealthed champions, however is can see those in brush, when suspended in the air.
Rappel can be used to get over terrain, as long as Elise can Rappel to a target.
Example: Use Rappel behind Ancient Golem's wall to grant vision. Then cast on Ancient Golem to descend in front of it.
This can be greatly used to steal neutral minions and objectives such as Baron Nashor or Dragon if positioned correctly.
Rappel used at the right moment can dodge projectiles and delayed aoe spells like Enchanted Crystal Arrow, Trueshot Barrage, Requiem, Absolute Zero, Time Bomb, Dark Matter and Explosive Cask.
Rappel does not cancel leash spells such as Drain, Soul Shackles, or Decrepify.
Elise is a deceptively effective pusher & counter jungle due to her spiderlings. Use Spider Form to take enemy jungle camps, towers, and other structures when the opportunity presents itself.